AbbVie Reports P-IV (IMMpulse) Study Results of Skyrizi (risankizumab) for Adult Patients with Moderate Plaque Psoriasis
Shots:
- The head-to-head P-IV study results published in British Journal of Dermatology evaluating Skyrizi vs Otezla in adult patients, showed that a higher proportion of patients achieved period A co-primary EPs of PASI 90 (55.9%) & sPGA 0/1 (75.4%) vs 5.1% & 18.4% with apremilast at 16wk.
- Patients achieved the 2EPs of PASI 75 at 16wk. was higher in risankizumab (84.7% vs 18.8%). At 52wk., patients re-randomized with risankizumab achieved period B 1EPs of PASI 90 (72.3% vs 2.6%) who failed to achieve PASI 75 after 16wks.
- Patients achieved the pre-specified EPs of PASI 90 (73.7%) & PASI 100 (63.6%) vs 4.5% & 2.7% after 52wks. & the safety profile was consistent with prior reported studies with no new safety signals. During periods A & B among the re-randomization arms, 6.8% & 5.2% discontinued treatment due to AEs
Ref: AbbVie | Image: AbbVie
Related News:- AbbVie Reports P-III Study (COMMAND) Results of Skyrizi (risankizumab) for the Treatment of Ulcerative Colitis
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